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The active ingredient of Aldactone tablets is Spironolactone. Spironolactone belongs to a particular group of medicines, known as aldosterone antagonists, which inhibit the action of the hormone aldosterone. One of the functions of aldosterone is to ensure that the body retains sodium. It forms part of a system that regulates the balance of fluids and salts in the body (‘RAAS’, renin angiotensin aldosterone system).
Spironolactone promotes the excretion of urine in patients in whom there is an accumulation of fluid in the tissues (oedema) or in the abdominal cavity (ascites) by increasing the amount of sodium (salt) excreted in the urine. Potassium loss as a possible consequence of using certain diuretics is reduced. The antihypertensive effect relies on the excretion of water and salt.
Aldactone is used in the treatment of high blood pressure and oedema. It treats oedema (fluid overload) associated with heart, liver, kidney or lung disease.
Direction to Use
Nausea, Vomiting, Leg cramps, Dizziness, Drowsiness, Confusion, Breast enlargement in male, Increased creatinine level in blood