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Sez contains Secnidazole as the active ingredient. Secnidazole is a synthetic derivative of the group of nitroimidazoles. Its antiparasitic activity affects Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis and Gardnerella vaginalis.
Secnidazole works by entering the microorganisms through diffusion and is reduced intracellularly by low oxidation-reduction potential ferredoxin which then result in DNA damage.
Sez is indicated for the treatment of intraintestinal and extraintestinal amebiasis (liver), intestinal diseases caused by Giardia lamblia (giardiasis or lambliasis), trichomoniasis (vaginitis and urethritis) and nonspecific vaginosis.
Direction to Use
This medicune usually does not cause severe adverse reactions, although have been reported occasionally adverse effects as decreased appetite , headache, discomfort, heartburn and gastric pain, nausea, vomiting, diarrhoea, constipation, dry mouth and bad taste (metallic) and vertigo. These effects are transient and do not require discontinuation of treatment.