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Ondem contains Ondansetron as the active ingredient which belongs to a group of medicines called anti-emetics, which help to stop you feeling or being sick. It is used to treat nausea (feeling sick) and vomiting (being sick) caused by some medical treatments, such as chemotherapy or radiotherapy for cancer (in adults and children). It is also used to prevent nausea and vomiting in patients following an operation (adults only).
Ondansetron is a selective serotonin 5-HT3 receptor antagonist. This drug works by inhibiting of 5-HT3 receptors present both centrally (medullary chemoreceptor zone) and peripherally (gastrointestinal tract). This inhibition of 5-HT3 receptors in turn inhibits the visceral afferent stimulation of the vomiting center, likely indirectly at the level of the area postrema, as well as through direct inhibition of serotonin activity within the area postrema and the chemoreceptor trigger zone.
Ondem is used in the treatment and prevention of nausea and vomiting.
Direction to Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ondem Tablet may be taken with or without food, but it is better to take it at a fixed time.
Common Side Effects of Ondem are Fatigue, Headache, Constipation, Diarrhoea, Decreased oxygen level in blood.