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Nexpro contains a medicine called Esomeprazole. This belongs to a group of medicines called ‘proton pump inhibitors’. They work by reducing the amount of acid that y our stomach produces. It is S-isomer of omeprazole that binds to H+/K+-exchanging ATPase (proton pump) in gastric parietal cells, interfering with the final step of acid release in the stomach. Thus, acidity in the stomach is decreased.
H.pylori eradication, GERD, Duodenal ulcers, Zollinger-Ellison Syndrome, NSAID-Induced Gastric Ulcer, Frequent Heartburn
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Common side effects(may affect up to 1 in 10 people): Headache, Effects on your stomach or gut: diarrhoea, stomach pain, constipation, wind (flatulence), Feeling sick (nausea) or being sick (vomiting), Benign polyps in the stomach.
Uncommon(may affect up to 1 in 100 people): Swelling of the feet and ankles, Disturbed sleep (insomnia), Dizziness, tingling feelings such as “pins and needles”, feeling sleepy, Spinning feeling (vertigo), Dry mouth, Skin rash, lumpy rash (hives) and itchy skin, Fracture of the hip, wrist or spine