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Naltima Tablet contains Naltrexone as the active ingredient which is an opioid antagonist. It works by blocking the euphoric feelings (highs) that you may experience after taking opiates and alcohol. This reduces craving and helps you remain off of them.
Naltrexone is a pure opiate antagonist and has little or no agonist activity. The mechanism of action of naltrexone in alcoholism is not understood, however, involvement of the endogenous opioid system is suggested by preclinical data. Naltrexone is thought to act as a competitive antagonist at µ, k and d receptors in the CNS, with the highest affintiy for the µ receptor. Naltrexone competitively binds to such receptors and may block the effects of endogenous opioids. This leads to the antagonization of most of the subjective and objective effects of opiates, including respiratory depression, miosis, euphoria and drug craving. The major metabolite of naltrexone, 6-ß-naltrexol, is also an opiate antagonist and may contribute to the antagonistic activity of the drug.
Naltima Tablet is used in the treatment of opioid dependence and alcohol dependence.
Direction to Use
Common Side Effects of Naltima are Injection site redness, Insomnia (difficulty in sleeping), Cold symptoms, Toothache, Increased liver enzymes.