• Tab. Mizest-15mg

Tab. Mizest-15mg

Requires Prescription
strip of 10 tablets
Generic Name: Mirtazapine
25 Ratings
Rs. 100

Additional Information

No Additional Information

Information about Tab. Mizest-15mg

Mizest contains Mirtazapine as the active ingredient which is a noradrenergic and specific serotonergic antidepressant used in the treatment of depression.

Mirtazapine acts as an antagonist at central pre-synaptic alpha(2)-receptors, inhibiting negative feedback to the presynaptic nerve and causing an increase in NE release. Blockade of heteroreceptors, alpha(2)-receptors contained in serotenergic neurons, enhances the release of 5-HT, increasing the interactions between 5-HT and 5-HT1 receptors and contributing to the anxiolytic effects of mirtazapine. Mirtazapine also acts as a weak antagonist at 5-HT1 receptors and as a potent antagonist at 5-HT2 (particularly subtypes 2A and 2C) and 5-HT3 receptors. Blockade of these receptors may explain the lower incidence of adverse effects such as anxiety, insomnia and nausea. Mirtazapine also exhibits significant antagonism at H1-receptors, resulting in sedation.




Depression, Post traumatic stress diorder (off label), Hot flashes (off label), Insomnia (off label)

Direction to Use

  • Take this medicine in the dose and duration as advised by your doctor.
  • Swallow it as a whole. Do not chew, crush or break it.
  • Mizest Tablet may be taken with or without food, but it is better to take it at a fixed time.
  • Do not drive unless you are feeling well as it may decrease alertness.
  • Avoid consuming alcohol when taking Mizest, as it may cause excessive drowsiness and calmness.
  • If your doctor asks you to stop Mizest, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly.

Side Effects

Common Side Effects are Sleepiness, Dryness in mouth, Increased appetite, Headache, Weight gain.

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