No Additional Information
Medigra Tablet contains Sildenafil as the active ingredient which is a phosphodiesterase-5 (PDE-5) inhibitor. It works by relaxing the blood vessels in your penis, thereby increasing blood flow into the penis on sexual stimulation. This helps you achieve and maintain a hard, erect penis suitable for sexual activity.
Sildenafil inhibits the cGMP-specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum located around the penis. Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and corpus cavernosal smooth muscle. This response is mediated by the release of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in smooth muscle cells. Cyclic GMP causes smooth muscle relaxation and increased blood flow into the corpus cavernosum. The inhibition of phosphodiesterase type 5 (PDE5) by sildenafil enhances erectile function by increasing the amount of cGMP.
Medigra Tablet is used in the treatment of erectile dysfunction.
Direction to Use
Common Side Effects are Flushing (sense of warmth in the face, ears, neck and trunk), Headache, Stiffness, Blurred vision.