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Tilstigmin contains Neostigmine as the active ingredient which a parasympathomimetic drug used to treat the symptoms of myasthenia gravis, glaucoma, urinary retention and in reversal of muscular block. It increases the levels of chemical messengers which allows free transmission of signals across the nerves and muscles.
Neostigmine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor. It inhibits acetylcholinesterase which is responsible for the degredation of acetylcholine. Hence, more acetylcholine is present. By interfering with the breakdown of acetylcholine, neostigmine indirectly stimulates both nicotinic and muscarinic receptors which are involved in muscle contraction. It does not cross the blood-brain barrier.
Tilstigmin is used in the treatment of myasthenia gravis, paralytic ileus, post-operative urinary retention and reversal of effect of skeletal muscle relaxant after surgery.
Direction to Use
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Nausea, Vomiting, Abdominal cramp, Diarrhoea, Excessive salivation