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Crestor contains Rosuvastatin as the active ingredient which is a selective and competitive inhibitor of HMG-CoA reductase , the rate limiting enzyme in cholesterol synthesis. It increases the number of hepatic LDL receptors on the cell surface ,enhancing uptake and catabolism of LDL. It also decreases apolipoprotein B, triglycerides and increases HDL.
Hyperlipedemia, primary hypercholesterolaemia (heterozygous Familial hypocholesterolaemia), mixed dyslipidaemia, homozygous familial hypercholesterolaemia, stroke prevention.
Direction to Use
Swallow each tablet whole with a drink of water. Take the tablet once daily. You can take it at any time of the day with or without food. Try to take your tablet at the same time every day to help you to remember it.
If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, miss out the forgotten dose. Do not take two doses at the same time to make up for a forgotten dose.
Common Side Effects are Headache, Stomach pain, Constipation, Feeling sick, Muscle pain, Weakness, Dizziness, Increased glucose level in blood.