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  • Cap. Premax-75mg

Cap. Premax-75mg

Requires Prescription
strip of 10 tablets
Generic Name: Pregabalin
25 Ratings
Rs. 150

Additional Information

No Additional Information

Information about Cap. Premax-75mg

Premax Capsule contains Pregabalin as the active ingredient which is an antiepileptic medication. It decreases pain and seizures by modulating calcium channel activity of the nerve cells.

Pregabalin binds presynaptically to the alpha2-delta subunit of the voltage-gated calcium channels in central nervous system tissues located in the brain and spinal cord. The mechanism of action has not been fully elucidated but studies suggest that pregabalin produces a disruption of calcium channel traficking or a reduction of calcium currents. The inhibition of subunits of voltage-gated calcium channels reduces calcium release which in order inhibits the release of several neurotransmitters. Studies also suggest that the descending noradrenergic and serotonergic pathways originating from the brainstem may be involved with the mechanism of pregabalin. Interestingly, although pregabalin is a structural derivative of inhibitory neurotransmitter gamma-aminobutyric acid (GABA), it does not bind directly to GABA or benzodiazepine receptors.

INGREDIENTS:

Pregabalin

Benifits:

Premax is used for the management of neuropathic pain associated with diabetic peripheral neuropathy or spinal cord injury, and postherpetic neuralgia.

Direction to Use

  • Take this medicine in the dose and duration as advised by your doctor.
  • Swallow it as a whole. Do not chew, crush or break it.
  • Premax Capsule may be taken with or without food, but it is better to take it at a fixed time.
  • It may cause sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Premax Capsule, as it may cause excessive sleepiness or drowsiness.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.

Side Effects

Common Side Effects of Premax are Sleepiness, Dizziness, Uncoordinated body movement, Fatigue. Its side effects are usually mild and go away by themselves.

Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.

Alternative Products
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Metro Hospital
For Doctor's Consultation Contact: +977 1 4721515. Metro Kathmandu Hospital